| Bioactivity | Apalutamide-d4 is a deuterium labeled Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1]. | ||||||||||||
| Name | Apalutamide-d4 | ||||||||||||
| CAS | 1638885-65-0 | ||||||||||||
| Formula | C21H11D4F4N5O2S | ||||||||||||
| Molar Mass | 481.46 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Clegg NJ, et al. ARN-509: a novel antiandrogen for prostate cancer treatment. Cancer Res. 2012 Mar 15;72(6):1494-503. |