Bioactivity | Antiviral agent 64 (Compound 12) is a diarylheptanoid that can be isolated from Alpinia officinarum. Antiviral agent 64 exhibits cytotoxicity in human neuroblastoma cell IMR-32 with an IC50 of 0.23 μM. Antiviral agent 64 exhibits antiviral efficacy, that inhibits RSV, poliovirus, measles virus, HSV-1, and influenza virus H1N1, with EC50 of 13.3, 3.7, 6.3, 5.7, and <10 μg/mL, respectively[1][2][3]. |
CAS | 1004319-60-1 |
Formula | C21H26O4 |
Molar Mass | 342.43 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sun, Yi; et al., New Cytotoxic Diarylheptanoids from the Rhizomes ofAlpinia officinarum. Planta Medica, 74(4), 427–431. [2]. Sawamura R, et al., Antiviral activities of diarylheptanoids against influenza virus in vitro. J Nat Med. 2010 Jan;64(1):117-20. [3]. Konno K, et al. Antiviral activities of diarylheptanoids isolated from Alpinia officinarum against respiratory syncytial virus, poliovirus, measles virus, and herpes simplex virus type 1 in vitro[J]. Natural product communications, 2011, 6(12): 1934578X1100601222. |