Bioactivity | Antiviral agent 36 (compound 27) is a potent dengue (DENV) and Zika (ZIKV) viruses inhibitor. Antiviral agent 36 inhibits replication of Zika and dengue virus with EC50s of 100 nM, 90 nM, 210 nM, and 120 nM for ZIKV-FLR, ZIKV-HN16, DENV-2, and DENV-3, respectively[1]. |
Name | Antiviral agent 36 |
Formula | C30H32N4O3 |
Molar Mass | 496.60 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Md Ashraf-Uz-Zaman, et al. Quinazolinone Compounds Have Potent Antiviral Activity against Zika and Dengue Virus. J Med Chem. 2023 Aug 10;66(15):10746-10760. |