| Bioactivity | Antiviral agent 23 (compound 11b) is an antiviral agent to enterovirus 71 (EV71) with an EC50 value of 94 nM. Antiviral agent 23 effectively suppresses the activity of METTL3/METTL14. Antiviral agent 23 can be used for the research of infection[1]. |
| Invitro | Antiviral agent 23 (0-100 μM) 抑制 CVA21 和 EV68 在 HeLa 细胞中的复制，其 EC50 值分别为 36.4 和 8.9 μM[1]。Antiviral agent 23 (100 μM) 抑制 METTL3/METTL14 的酶活，至 74.45%[1]。Antiviral agent 23 (0-100 μM) 抑制 EV71 毒株 BrCr 在 RD 细胞中的复制，EC50 值为 94 nM[1]。 |
| Name | Antiviral agent 23 |
| CAS | 35940-03-5 |
| Formula | C18H21N5O4 |
| Molar Mass | 371.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Salerno M, et al. Rational design of novel nucleoside analogues reveals potent antiviral agents for EV71. Eur J Med Chem. 2022 Nov 24;246:114942. |
Antiviral agent 23
CAS: 35940-03-5 F: C18H21N5O4 W: 371.39
Antiviral agent 23 (compound 11b) is an antiviral agent to enterovirus 71 (EV71) with an EC50 value of 94 nM. Antiviral
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