| Bioactivity | Antitumor photosensitizer-4 (compound 10b) is a potent tyrosine kinase inhibitor (TKI) targeting ABCG2. Antitumor photosensitizer-4 is a photosensitizer (PS) consisting of a conjugate of dasatinib (HY-10181) and imatinib (HY-15463). Antitumor photosensitizer-4 induces apoptosis and ROS production and exhibits strong phototoxicity to HepG2 and B16-F10 cells[1]. |
| Invitro | Antitumor photosensitizer-4 0 --> Antitumor photosensitizer-4 相关抗体: |
| In Vivo | Antitumor photosensitizer-4 |
| Name | Antitumor photosensitizer-4 |
| Formula | C65H77ClN12O11S |
| Molar Mass | 1269.90 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Huang F, et al. Novel chlorin e6-based conjugates of tyrosine kinase inhibitors: Synthesis and photobiological evaluation as potent photosensitizers for photodynamic therapy. Eur J Med Chem. 2023 Sep 5;261:115787.. . |
Antitumor photosensitizer-4
CAS: F: C65H77ClN12O11S W: 1269.90
Antitumor photosensitizer-4 (compound 10b) is a potent tyrosine kinase inhibitor (TKI) targeting ABCG2. Antitumor photos
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