Bioactivity | Antitumor agent-97 (compound 42) is an anticancer agent. Antitumor agent-97 can effectively inhibit the proliferation and autophagy of MGC 803 cells, and induce apoptosis. Antitumor agent-97 also enhances ROS accumulation in MGC 803 cells. Antitumor agent-97 can be used in cancer research[1]. |
Invitro | Antitumor agent-97 (Compound 42; 0-200 μM; 24 h) 以浓度依赖的方式抑制 MGC 803 细胞的活力,其 IC50 值为 20.921 μM[1]。Antitumor agent-97 (20 μM; 24 h) 减少 MGC 803 细胞的增殖[1]。Antitumor agent-97 (20 μM; 24 h) 在 MGC 803 细胞中显示出诱导细胞凋亡,并抑制细胞自噬的活性[1]。Antitumor agent-97 (20 μM; 0-24 h) 增强 MGC 803 细胞中 ROS 的积累[1]。 Cell Viability Assay[1] Cell Line: |
Name | Antitumor agent-97 |
CAS | 2654024-16-3 |
Formula | C24H34O3 |
Molar Mass | 370.52 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Mao XD, et al. Synthesis and Bioactivity Evaluation of Nepetaefolin F and Its Analogues. ACS Omega. 2023 Apr 12;8(16):14830-14840. |