| Bioactivity | Antitumor agent-23 is a potent anti-cancer agent with GI50s of 38, 48, 5, 27, 80, and 28 nM for lymphoma cell line GRANTA-519, KARPAS-422, KARPAS-299, RAMOS, DAUDI, and RAJI, respectively. Antitumoral activity[1]. |
| Invitro | Antitumor agent-23 (0.001-100 μM; 5 days) inhibits lymphoma cells proliferation[1].Antitumor agent-23 (2-70 nM; 72 hours) induces p53 protein expression and p53 lysine 382 acetylation (K382Ac-p53) in HPV-positive cervical cancer cell[1]. Cell Proliferation Assay[1] Cell Line: |
| Name | Antitumor agent-23 |
| CAS | 2355185-12-3 |
| Formula | C28H50N4O4 |
| Molar Mass | 506.72 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Marc Labelle, et al. 1 -(piperidinocarbonylmethyl)-2-oxopiperazine derivatives for treating cancer. WO2019118973A1. |
Antitumor agent-23
CAS: 2355185-12-3 F: C28H50N4O4 W: 506.72
Antitumor agent-23 is a potent anti-cancer agent with GI50s of 38, 48, 5, 27, 80, and 28 nM for lymphoma cell line GRANT
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