Antitumor agent-127

CAS: F: C86H107N15O18S W: 1670.92

Antitumor agent-127 (compound 1) is a parent macrocyclic peptide. Antitumor agent-127 displays nanomolar cell-based bind

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Bioactivity	Antitumor agent-127 (compound 1) is a parent macrocyclic peptide. Antitumor agent-127 displays nanomolar cell-based binding to ROR1 and relatively good internalization in 786-O and MDA-MB-231 tumor cell lines[1].
Invitro	Antitumor agent-127 (compound 1) 不会诱导 Mia PaCa-2 细胞凋亡，Mia PaCa-2 细胞是一种模型胰腺肿瘤细胞系，细胞表面 ROR1 表达水平相对较低[1]。 0 --> Antitumor agent-127 相关抗体:
Name	Antitumor agent-127
Formula	C86H107N15O18S
Molar Mass	1670.92
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Qiao JX, et al. Exploration of macrocyclic peptide binders to the extracellular CRD domain of human receptor tyrosine kinase-like orphan receptor 1 (ROR1). Bioorg Med Chem Lett. 2023 Dec 13;98:129589.

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