PeptideDB

Antitumor agent-111

CAS: F: C34H29ClF2N6O5 W: 675.08

Antitumor agent-111 (compound 46) is an c-Met kinase inhibitor (IC50=46 nM) with antitumor and antiproliferative activit
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Bioactivity Antitumor agent-111 (compound 46) is an c-Met kinase inhibitor (IC50=46 nM) with antitumor and antiproliferative activity. Antitumor agent-111 arrests cell cycle at G0/G1 phase, and induces apoptosis[1].
Target c-Met
Name Antitumor agent-111
Formula C34H29ClF2N6O5
Molar Mass 675.08
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Dai J, et al. Design, synthesis and biological evaluation of 4-(4-aminophenoxy)picolinamide derivatives as potential antitumor agents. Eur J Med Chem. 2023 Sep 5;257:115499.