| Bioactivity | Antituberculosis agent-8 (Compound 9i) is an antitubercular agent with an MIC of 3.53 μM (1.6 μg/mL) against M. tuberculosis H37Rv. Antituberculosis agent-8 also shows good antifungal activity against A. niger with an MIC of 62.50 μM[1]. |
| Invitro | Antituberculosis agent-8 (Compound 9i) shows antimicrobial activity with MICs of 3.53, 62.50, 125, 250 and 250 μM against M. tuberculosis H37Rv, A. Niger, C. albicans, S. albus, B. subtilis, respectively[1]. |
| Name | Antituberculosis agent-8 |
| CAS | 2874263-74-6 |
| Formula | C25H19F3N2O3 |
| Molar Mass | 452.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shinde A, et al. Synthesis, Characterization, and Antimicrobial Activity Screening of Some Novel 3-(2-(3-(Substituted benzyloxy)oxetan-3-yl)-3-fluorophenoxy)-8-fluoro-2-methylquinoline Derivatives as Potential Antimycobacterial Agents. ACS Omega. 2022 Dec 6;7(50):47096-47107. |
Antituberculosis agent-8
CAS: 2874263-74-6 F: C25H19F3N2O3 W: 452.43
Antituberculosis agent-8 (Compound 9i) is an antitubercular agent with an MIC of 3.53 μM (1.6 μg/mL) against M. tuberc
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