PeptideDB

Antitubercular agent-35

CAS: F: C19H13ClN4O2S W: 396.85

Antitubercular agent-35 (compound 42l) is an antitubercular agent. Antitubercular agent-35 inhibits the growth of MtbH37
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity Antitubercular agent-35 (compound 42l) is an antitubercular agent. Antitubercular agent-35 inhibits the growth of MtbH37Rv and M. Marinum with MIC90 values of 1.25 and 2 μg/mL, respectively. Antitubercular agent-35 shows the ability of escaping metabolic degradation by human liver microsomes. Antitubercular agent-35 can be used for the research of tuberculosis[1].
Invitro Antitubercular agent-35 (0-20 μg/mL; 3-4 d) shows inhibitory effect to MtbH37Rv and M. Marinum with MIC90 values of 1.25 and 2 μg/mL, respectively[1].
Name Antitubercular agent-35
Formula C19H13ClN4O2S
Molar Mass 396.85
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Girardini M, et al. Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization. Eur J Med Chem. 2023 Jan 5;245(Pt 2):114916.