Antitubercular agent 34_product_DataBase

Bioactivity	Antitubercular agent 34 (compound 42g) is an antitubercular agent. Antitubercular agent 34 inhibits the growth of MtbH37Rv with a MIC90 value of 1.25 μg/mL with the ability of escaping metabolic degradation by human liver microsomes. Antitubercular agent 34 can be used for the research of tuberculosis[1].
Invitro	Antitubercular agent 34 (0-20 μg/mL; 3-4 d) 对 MtbH37Rv 有抑制作用，MIC90 值为 1.25 μg/mL[1]。Antitubercular agent 34 (0-100 μM; 3 d) 抑制人单核细胞 THP-I 细胞系的生长[1]。 Cell Viability Assay[1] Cell Line:
Name	Antitubercular agent 34
Formula	C19H14N4O2S
Molar Mass	362.41
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Girardini M, et al. Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization. Eur J Med Chem. 2023 Jan 5;245(Pt 2):114916.

PeptideDB