| Bioactivity | Antitrypanosomal agent 9 (compound 1) is a potent antitrypanosomal agent. Antitrypanosomal agent 9 shows inhibitory activity against T. b. brucei, with an IC50 of 1.15 μM. Antitrypanosomal agent 9 can be used for human African trypanosomiasis (HAT) research[1]. | ||||||||||||
| Invitro | Antitrypanosomal agent 9 (compound 1) shows inhibitory activity against T. b. rhodesiense, T. cruzi, L. donovani, and P. falciparum, with IC50 values of 0.985 ± 0.076, 107 ± 34.5, 35.7 ± 6.22, and 22.3 ± 1.06 μM, respectively[1]. Antitrypanosomal agent 9 shows cytotoxicity in L6 cells, with an IC50 of 186 ± 94.2 μM[1]. | ||||||||||||
| Name | Antitrypanosomal agent 9 | ||||||||||||
| CAS | 438474-67-0 | ||||||||||||
| Formula | C22H27NO3 | ||||||||||||
| Molar Mass | 353.45 | ||||||||||||
| Appearance | Powder | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Manos-Turvey Alexandra, et al. Synthesis and evaluation of phenoxymethylbenzamide analogues as anti-trypanosomal agents. Med Chem Commun. 2015, 6(3), 403–406. |
Antitrypanosomal agent 9
CAS: 438474-67-0 F: C22H27NO3 W: 353.45
Antitrypanosomal agent 9 (compound 1) is a potent antitrypanosomal agent. Antitrypanosomal agent 9 shows inhibitory acti
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