| Bioactivity | Antitrypanosomal agent 4 (compound 19) is a potent and blood-brain barrier permeable antitrypanosomal agent. Antitrypanosomal agent 4 has good activity against Trypanosoma cruzi (T. cruzi) and Trypanosoma brucei brucei (T. b. brucei) with IC50s of 1.2 μM and 70 nM, respectively[1]. |
| Target | IC50: 1.2 μM (T. cruzi), 70 nM (T. b. brucei) |
| Name | Antitrypanosomal agent 4 |
| CAS | 2456427-48-6 |
| Formula | C18H14ClN3O5S |
| Molar Mass | 419.84 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Fersing C, Boudot C, Castera-Ducros C, et al. 8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi. Eur J Med Chem. 2020;202:112558. |
Antitrypanosomal agent 4
CAS: 2456427-48-6 F: C18H14ClN3O5S W: 419.84
Antitrypanosomal agent 4 (compound 19) is a potent and blood-brain barrier permeable antitrypanosomal agent. Antitrypano
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