| Bioactivity | Antitrypanosomal agent 11 is an antitrypanosomal agent that inhibits Trypanosoma cruzi with an IC50 of 0.23 μM[1]. |
| Target | IC50: 0.23 μM (Trypanosoma cruzi) |
| Invitro | Antitrypanosomal agent 11 (compound 53) 对哺乳动物细胞具有一定毒性、可接受的小鼠肝微粒体 (MLM) 清除率[1]。 |
| Name | Antitrypanosomal agent 11 |
| Formula | C16H10F6N6O |
| Molar Mass | 416.28 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Celso de Oliveira Rezende Júnior, et al. Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease.Eur J Med Chem. 2022 Nov 15;246:114925. |