| Bioactivity | Antitrypanosomal agent 10 is an antitrypanosomal agent that inhibits Trypanosoma cruzi with an IC50 of 0.28 μM[1]. |
| Target | IC50: 0.28 μM (Trypanosoma cruzi) |
| Invitro | Antitrypanosomal agent 10 (compound 46) 显示出对哺乳动物细胞良好的选择性、可接受的小鼠肝微粒体 (MLM) 清除率和亲脂性。 |
| Name | Antitrypanosomal agent 10 |
| Formula | C17H9F6N5O |
| Molar Mass | 413.28 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Celso de Oliveira Rezende Júnior, et al. Hit-to-lead optimization of a 2-aminobenzimidazole series as new candidates for chagas disease.Eur J Med Chem. 2022 Nov 15;246:114925. |