| Bioactivity | Antiproliferative agent-60 (8c) is a 11-Azaartemisinin derivative with superior anticancer activities. Antiproliferative agent-60 shows IC50 values of 7.7 μM, 42.5 μM, and 15.5 μM for epidermoid carcinoma (KB), HepG2, and A549 cells, respectively. Antiproliferative agent-60 exhibits significant tumor selectivity, up to 32-fold higher compared to Hek293 normal cells[1]. |
| Formula | C24H29BrN4O4 |
| Molar Mass | 517.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Dung Tien Nguyen, et al. 11-Azaartemisinin derivatives bearing halogenated aromatic moieties: Potent anticancer agents with high tumor selectivity. Bioorg Med Chem Lett. 2024 Sep 18:113:129969. |
Antiproliferative agent-60
CAS: F: C24H29BrN4O4 W: 517.42
Antiproliferative agent-60 (8c) is a 11-Azaartemisinin derivative with superior anticancer activities. Antiproliferative
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