| Bioactivity | Antiproliferative agent-6 (compound 8a) is a potent antitumor agent. Antiproliferative agent-6 has antiproliferative activity against cancer cell lines HCT116, MCF-7, H460 and non-tumor aneuploid immortal keratinocyte HaCaT cells with GI50s of 0.5 μM, 2 μM, 0.7 μM and 3.5 μM, respectively[1]. |
| Target | GI50: 0.5 μM (HCT116), 2 μM (MCF-7), 0.7 μM (H460), 3.5 μM (HaCaT) |
| Name | Antiproliferative agent-6 |
| CAS | 2389016-82-2 |
| Formula | C21H14ClFN6 |
| Molar Mass | 404.83 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Meščić Macan A, et al. Synthesis, antiproliferative activity and DNA/RNA-binding properties of mono- and bis-(1,2,3-triazolyl)-appended benzimidazo[1,2-a]quinoline derivatives. Eur J Med Chem. 2020;185:111845. |
Antiproliferative agent-6
CAS: 2389016-82-2 F: C21H14ClFN6 W: 404.83
Antiproliferative agent-6 (compound 8a) is a potent antitumor agent. Antiproliferative agent-6 has antiproliferative act
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