| Bioactivity | Antiproliferative agent-50 (compound 10b) is EGFR-TK inhibitor with the IC50 of 0.16 μM. Antiproliferative agent-50 inhibits cell growth[1]. |
| Invitro | Antiproliferative agent-50 (compound 10b) 抑制细胞增殖，对 HCT116、HePG-2 和 MCF7的 IC50 值分别为9.94 μM、6.32 μM和8.11 μM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Antiproliferative agent-50 相关抗体: |
| Formula | C22H19N3O3 |
| Molar Mass | 373.40 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Serag MI, et al. M. New oxadiazole and pyrazoline derivatives as anti-proliferative agents targeting EGFR-TK: design, synthesis, biological evaluation and molecular docking study. Sci Rep. 2024;14(1):5474. Published 2024 Mar 5. |
Antiproliferative agent-50
CAS: F: C22H19N3O3 W: 373.40
Antiproliferative agent-50 (compound 10b) is EGFR-TK inhibitor with the IC50 of 0.16 μM. Antiproliferative agent-50 inh
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