Antiproliferative agent-48_product_DataBase

Bioactivity	Antiproliferative agent-48 (compound PC-A1) shows selective antiproliferative activity against triple-negative breast cancer (TNBC) cells[1].
Invitro	Antiproliferative agent-48 (5-50 μM) 抑制癌细胞 MDA-MB-231 (TNBC)、MCF-7、A549、KB (HeLa 衍生物) 和 KB-VIN 的增殖，IC50 分别为 5.4, 18, 19, 15 和 19 μM[1]。Antiproliferative agent-48 (5-50 μM) 在 G2/M 期阻滞细胞周期[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Antiproliferative agent-48 相关抗体: Cell Proliferation Assay[1] Cell Line:
CAS	1621594-62-4
Formula	C14H17BrO3
Molar Mass	313.19
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Maeda S, et al., Total Synthesis of a TNBC-Selective Cytotoxic Bromo Nor-eremophilane, PC-A, and Its Preliminary Structure-Activity Relationships. J Nat Prod. 2024 Mar 4. [2]. Maeda S, et al., Total Synthesis of a TNBC-Selective Cytotoxic Bromo Nor-eremophilane, PC-A, and Its Preliminary Structure-Activity Relationships. J Nat Prod. 2024 Mar 4.

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