Antiproliferative agent-43_product_DataBase

Bioactivity	Antiproliferative agent-43 (Compound e4 ) has notable cytotoxic effects against cancer cell lines and causes apoptosis by stopping the cell cycle at G1 phase[1].
Invitro	Antiproliferative agent-43 (0, 1.23, 2.45 , 2.90 μM, 48 h) 在 K562 细胞中引起 G1 期细胞周期阻滞，并伴有细胞核形态异常[1]。Antiproliferative agent-43 (0, 1.23, 2.45 , 2.90 μM, 48 h) 在 K562 细胞中通过线粒体途径诱导细胞凋亡[1]。 0 --> Antiproliferative agent-43 相关抗体: Cell Cycle Analysis[1] Cell Line:
Name	Antiproliferative agent-43
Formula	C45H57NO6S2
Molar Mass	772.07
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Gao X, et al. Discovery of sinomenine/8-Bis(benzylthio)octanoic acid hybrids as potential anti-leukemia drug candidate via mitochondrial pathway. Bioorg Med Chem Lett. 2023 Nov 7;97:129545.

PeptideDB