| Bioactivity | Antiproliferative agent-4 (compound 2y) has excellent anti-proliferative activity against certain cancer cell lines. Antiproliferative agent-4 reduces the mitochondrial membrane potential, and increases the apoptosis rate and the level of ROS on EC109. Antiproliferative agent-4 inhibits tumour growth in nude mice, with low toxicity[1]. |
| Invitro | Antiproliferative agent-4 has inhibitory activity against cancer cell lines EC109, TE-1, MGC-803 and MCF-7 with IC50s of 0.13 ± 0.01 μM, 0.27 ± 0.02 μM, 0.20 ± 0.01 μM and 0.35 ± 0.03 μM[1]. |
| Name | Antiproliferative agent-4 |
| Formula | C29H35ClO8 |
| Molar Mass | 547.04 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |