Bioactivity | Antiproliferative agent-37 (compound 10J) shows anti-proliferative effect by arresting the cells at the G2/M phase of the cell cycle[1]. |
Invitro | Antiproliferative agent-37 (compound 10J) 对A431、HT1080、MCF-7、MDA-MB-231和AG01523细胞株显示出细胞毒性/细胞抑制作用,IC50值分别为0.013±0.004、0.014±0.008、0.14±0.04、0.018±0.009、56.3±4.3 μM[1]。 0 --> Antiproliferative agent-37 相关抗体: |
Name | Antiproliferative agent-37 |
CAS | 2989275-31-0 |
Formula | C21H17FN2O2 |
Molar Mass | 348.37 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Lougiakis N, et al. Synthesis, cytotoxic activity evaluation and mechanistic investigation of novel 3,7-diarylsubstituted 6-azaindoles. Eur J Med Chem. 2023 Sep 13;261:115804. |