Antiproliferative agent-20

CAS: 1344715-94-1 F: C23H18N2O6 W: 418.40

Antiproliferative agent-20 is a potent and orally active anticancer agent. Antiproliferative agent-20 exhibits antiproli

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Bioactivity	Antiproliferative agent-20 is a potent and orally active anticancer agent. Antiproliferative agent-20 exhibits antiproliferative and anti-angiogenic activities[1].
Invitro	Antiproliferative agent-20 (compound 5) (3.125 -50.0 μM; 24-96 h) 以剂量依赖的方式抑制 Bel-7402 细胞的增殖[1]。
In Vivo	Antiproliferative agent-20 (10-40 μg/egg) 抑制鸡尿囊绒毛膜 (CAM) 的血管生成[1]。Antiproliferative agent-20 (3.2 g/kg; p.o.) 在两周内未显示小鼠死亡或毒性迹象[1]。Antiproliferative agent-20 (24 h)在 37℃ 人工胃液和人工肠液中不发生水解[1]。
Name	Antiproliferative agent-20
CAS	1344715-94-1
Formula	C23H18N2O6
Molar Mass	418.40
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. WANG PL, et, al. Synthesis and Antitumor Evaluation of One Novel Tetramethylpyrazine-Rhein Derivative. Asian Journal of Chemistry (2013), 25(9), 4885-4888.

Cys-Arg-Gly-Asp-Phe-Pro-Ala-Ser-Ser-Cys (Disulfide bridge:cys1-cys10)

N1,N1,N3,N3-Tetramethylpropane-1,3-diamine-d18