| Bioactivity | Antiproliferative agent-19 (compound 4a) is an anti-cancer agent that exerts anti-proliferative effects on lung cancer cells by inducing apoptosis. antiproliferative agent-19 also induces cell cycle arrest in the G2/M phase[1]. |
| Invitro | Antiproliferative agent-19 (0-50 µM; 72 h) 显著抑制人非小细胞肺癌和结肠癌细胞的生存能力[1]。Antiproliferative agent-19 (11.33 µM; 24, 48, and 72 h) 诱导 A549 细胞的亚 G1 期细胞周期停滞[1]。Antiproliferative agent-19 (11.33 µM; 6, 24 and 48 h) 在 A549 细胞中通过内在和外在途径诱导细胞凋亡[1]。 Cell Cytotoxicity Assay[1] Cell Line: |
| Name | Antiproliferative agent-19 |
| Formula | C26H23NO |
| Molar Mass | 365.47 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |