Antiparasitic agent-14_product_DataBase

Bioactivity	Antiparasitic agent-14 is a potemt antiparasitic agent. Antiparasitic agent-14 shows cytotoxicity and antiparasitic activity. Antiparasitic agent-14 inhibits the growth of trypomastigote and amastigote[1].
Invitro	Antiparasitic agent-14 (compound 27) 具有细胞毒性和抗寄生虫活性，RAW 264.7 细胞的 CC50 值为 295.6 µM，对克氏锥虫 (T. cruzi) 密鞭和无尾鞭的 IC50 值分别为 1.5，0.89 µM[1]。Antiparasitic agent-14 具有抗寄生虫活性，对亚马逊利什曼原虫 (L. amazonensis) 的前鞭毛体和无鞭毛体形式的 IC50 值分别为 22.4、5.70 µM[1]。
Name	Antiparasitic agent-14
Formula	C19H20N4OS
Molar Mass	352.45
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Conceição JMD, et al. Structural design, synthesis, and anti-Trypanosomatidae profile of new Pyridyl-thiazolidinones. Eur J Med Chem. 2023 Apr 6;254:115310.

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