| Bioactivity | Antimycobacterial agent-8 (Compound 49) is an inhibitor for DNA gyrase. Antimycobacterial agent-8 exhibits antibacterial activity against Mycobacterium tuberculosis and M. abscessus with MIC90 of 2.5 μM and 0.63 μM. Antimycobacterial agent-8 exhibits good plasma protein binding ability in mice[1]. |
| Formula | C21H22Cl2N4O4S |
| Molar Mass | 497.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Sterle M, et al., Development of narrow-spectrum topoisomerase-targeting antibacterials against mycobacteria. Eur J Med Chem. 2024 Jul 19;276:116693. |
Antimycobacterial agent-8
CAS: F: C21H22Cl2N4O4S W: 497.39
Antimycobacterial agent-8 (Compound 49) is an inhibitor for DNA gyrase. Antimycobacterial agent-8 exhibits antibacterial
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