| Bioactivity | Antimalarial agent 16 (Compound 4h) is a parasite inhibitor. Antimalarial agent 16 shows antimalarial activity, and can inhibit P. falciparum parasite growth (IC50=2.0 nM)[1]. |
| Target | IC50: 2.0 nM (P. falciparum) |
| In Vivo | Antimalarial agent 16 (i.p.; 40 or 200 mg/kg; once daily; 4 days) exhibits significant in vivo antimalarial effects[1]. Animal Model: |
| Name | Antimalarial agent 16 |
| CAS | 2773408-33-4 |
| Formula | C30H32N2O6 |
| Molar Mass | 516.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nobuo Cho, et al. New antimalarials identified by a cell-based phenotypic approach: Structure-activity relationships of 2,3,4,9-tetrahydro-1H-β-carboline derivatives possessing a 2-((coumarin-5-yl)oxy)alkanoyl moiety. Bioorg Med Chem. 2022 Jul 15;66:11683 |
Antimalarial agent 16
CAS: 2773408-33-4 F: C30H32N2O6 W: 516.58
Antimalarial agent 16 (Compound 4h) is a parasite inhibitor. Antimalarial agent 16 shows antimalarial activity, and can
Data collection：peptidedb@qq.com
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