| Bioactivity | Antimalarial agent 15 (Compound 4e) is a parasite inhibitor. Antimalarial agent 15 shows antimalarial activity, and can inhibit P. falciparum 3D7 parasite growth (IC50=20 nM)[1]. |
| Target | IC50: 20 nM (P. falciparum 3D7) |
| Invitro | Antimalarial agent 15 shows no cytotoxicity against mammalian cells or affects the growth of bacteria and fungi up to 30 μM[1]. |
| Name | Antimalarial agent 15 |
| CAS | 956928-33-9 |
| Formula | C29H30N2O6 |
| Molar Mass | 502.56 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nobuo Cho, et al. New antimalarials identified by a cell-based phenotypic approach: Structure-activity relationships of 2,3,4,9-tetrahydro-1H-β-carboline derivatives possessing a 2-((coumarin-5-yl)oxy)alkanoyl moiety. Bioorg Med Chem. 2022 Jul 15;66:11683 |
Antimalarial agent 15
CAS: 956928-33-9 F: C29H30N2O6 W: 502.56
Antimalarial agent 15 (Compound 4e) is a parasite inhibitor. Antimalarial agent 15 shows antimalarial activity, and can
Data collection：peptidedb@qq.com
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