| Bioactivity | Antimalarial agent 14 (Compound N3) is a potent inhibitor of mitochondrial electron transport. Antimalarial agent 14 can serve as an anti-malarial agent[1]. |
| Target | mitochondrial electron transport |
| Invitro | Antimalarial agent 14 (Compound N3) (0-400 μM, 48 h) inhibits P. falciparum with limited cytotoxicity against human cells[1].Antimalarial agent 14 inhibits P. falciparum mitochondrial membrane potential with an IC50ΔΨmit of 16 μM[1]. Cell Cytotoxicity Assay[1] Cell Line: |
| Name | Antimalarial agent 14 |
| CAS | 1150-59-0 |
| Formula | C16H10O3 |
| Molar Mass | 250.25 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Schuck DC, et al. Biological evaluation of hydroxynaphthoquinones as anti-malarials. Malar J. 2013 Jul 10;12:234. |
Antimalarial agent 14
CAS: 1150-59-0 F: C16H10O3 W: 250.25
Antimalarial agent 14 (Compound N3) is a potent inhibitor of mitochondrial electron transport. Antimalarial agent 14 can
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