Bioactivity | Antifungal agent 87(10) acts as a highly potent PDT antimycotic photosensitizer (PDT-IC50 = 1 nM for T. rubrum)[1]. |
Target | PDT-IC50 = 1 nM for T. rubrum |
Invitro | Antifungal agent 87(10)在牛蹄角蛋白膜中渗透深度约为50-70 μm,具有显著的亲角蛋白特征[1]。Antifungal agent 87(10)通过角蛋白穿透波长(~500 nm)的光辐射会产生局部抗真菌作用[1]。 0 --> Antifungal agent 87 相关抗体: |
Name | Antifungal agent 87 |
CAS | 692730-21-5 |
Formula | C14H14O4 |
Molar Mass | 246.26 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Baier J, et al.Novel Henna-Related Naphthazarine Photosensitizers for an Effective Photodynamic Therapy of Onychomycosis. ACS Pharmacology & Translational Science. 2023 Nov. |