Bioactivity | Antifungal agent 122 (compound 201) is a potent and broad-spectrum antifungal agent. Antifungal agent 122 prevents fungal phase transition and the formation of fungal biofilm. Antifungal agent 122 inhibits CYP3A4-M and CYP3A4-M enzyme activity with IC50 values of 2.11, 4.53 µM. Antifungal agent 122 shows no cytotoxicity[1]. |
CAS | 3054212-80-2 |
Formula | C28H24F4N4O |
Molar Mass | 508.51 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sun Y, et al. Discovery of highly potent triazole derivatives with broad-spectrum antifungal activity based on Iodiconazole. Eur J Med Chem. 2024 Oct 9;280:116949. |