Bioactivity | Antidiabetic agent 5 (compound S1) is a antidiabetic agent. Antidiabetic agent 5 inhibits the activity of α-glucosidase and α-amylase with IC50 values of 3.91, 8.89 µM, respectively. Antidiabetic agent 5 decreases sugar levels. Antidiabetic agent 5 has the potential for the research of type-II diabetes[1]. |
Target | IC50: 3.91 µM (α-glucosidase); 8.89 µM (α-amylase) |
In Vivo | Antidiabetic agent 5 (3.9, 7.8 mg/kg) 可降低糖尿病小鼠的血糖水平[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: |
CAS | 2152667-21-3 |
Formula | C17H15N3O4S |
Molar Mass | 357.38 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Taj S, et al. The antihyperglycemic potential of pyrazolobenzothiazine 1, 1-dioxide novel derivative in mice using integrated molecular pharmacological approach. Sci Rep. 2024 Apr 2;14(1):7746. |