| Bioactivity | Antidiabetic agent 2 (Compound 56) is a glucose-uptake promoter. Antidiabetic agent 2 inhibits DPP-4, PTP-1B, α-amylase, and α-glucosidase with IC50s of 0.036, 0.042, 0.241, 0.185 μM. Antidiabetic agent 2 decreases blood glucose levels[1]. |
| Target | 0.036, 0.042, 0.241, 0.185 μM (DPP-4, PTP-1B, α-amylase, and α-glucosidase) |
| Name | Antidiabetic agent 2 |
| Formula | C25H21N5O9S2 |
| Molar Mass | 599.59 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shah M, et al. SAR and lead optimization of (Z)-5-(4-hydroxy-3-methoxybenzylidene)-3-(2-morpholinoacetyl)thiazolidine-2,4-dione as a potential multi-target antidiabetic agent. Eur J Med Chem. 2023 Oct 5;258:115591. |