Bioactivity | Antidepressant agent 4 is an orally active antidepressant agent. Antidepressant agent 4 exhibits antidepressant, anxiolytic, performance enhancing and nootropic activities[1]. |
Invitro | 分子建模研究表明 Antidepressant agent 4 (化合物 5f) 似乎通过结合 GABA-A,褪黑激素和 Sigma-1 受体发挥作用[1]。 |
In Vivo | Antidepressant agent 4 (化合物 5f) (10 mmol/kg; 口服灌胃) 增加运动和暂定搜索活动,以及更高的相互作用频率,并在受社会抑郁症影响的小鼠的蔗糖偏好测试中得到更好的结果[1]。 |
Name | Antidepressant agent 4 |
Formula | C19H38ClN5O2S |
Molar Mass | 436.06 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Fioravanti R, et, al. Pyrimidine thioethers: A novel class of antidepressant agents, endowed with anxiolytic, performance enhancing and nootropic activity. Eur J Med Chem. 2023 Jan 5;245(Pt 2):114902. |