Bioactivity | Anticancer agent 89 is a benzothiazole-2-thiophene S-glycoside derivative with antitumor activity, has high inhibition against the three cell line from ovarian cancer (OVCAR-4), renal cancer (A498), and melanoma (SK-MEL-5)[1]. |
Invitro | Anticancer agent 89 (compound 6f) (0.01 mM; 24 h) has low cytotoxicity, shows high inhibition against three cell lines, SK-MEL-5, OVCAR-4, and A498[1]. Cell Cytotoxicity Assay[1] Cell Line: |
Name | Anticancer agent 89 |
Formula | C32H29BrN2O10S3 |
Molar Mass | 777.68 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Lei H, et al. Discovery of Novel, Potent, and Selective Small-Molecule Menin-Mixed Lineage Leukemia Interaction Inhibitors through Attempting Introduction of Hydrophilic Groups. J Med Chem. 2022 Oct 13;65(19):13413-13435. |