| Bioactivity | Anticancer agent 74 is a moderate anticancer agent. Anticancer agent 74 has lower selectivity and cytotoxicity than doxorubicin to normal cell[1]. |
| Invitro | Anticancer agent 74 has low cytotoxicity in HepG2 (IC50: 72.27 μM), A549 (IC50: 70.79 μM), HuCCA-1 (IC50: 70.42 μM) and MOLT-3 (IC50: 20.71 μM) cell lines. Anticancer agent 74 has low selectivity in HepG2 (IC50: 0.88 μM), A549 (IC50: 5.08 μM), HuCCA-1 (IC50: 5.11 μM) and MOLT-3 (IC50: 17.39 μM) cell lines[1]. Cell Cytotoxicity Assay Cell Line: |
| Name | Anticancer agent 74 |
| CAS | 2242503-82-6 |
| Formula | C25H21NO |
| Molar Mass | 351.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bhornrawin Akkachairin, et al. Synthesis of neocryptolepines and carbocycle-fused quinolines and evaluation of their anticancer and antiplasmodial activities, Bioorg Chem. 2020 May;98:103732. |
Anticancer agent 74
CAS: 2242503-82-6 F: C25H21NO W: 351.44
Anticancer agent 74 is a moderate anticancer agent. Anticancer agent 74 has lower selectivity and cytotoxicity than doxo
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