Bioactivity | Anticancer agent 263 (compound 7) is a potent anticancer agent. Anticancer agent 263 binds to the G-quadruplex DNA (G4) sequence 22-mer Pu22, a mimic of c-Myc DNA. Anticancer agent 263 is a structure modulator, showcasing a significant enhancement in protein α-helix formation and the capability to form supramolecular network. Anticancer agent 263 shows no cytotoxicity[1]. |
Formula | C13H20N2O6 |
Molar Mass | 300.31 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Hayarpi Simonyan, et al. Exploring the binding of c-Myc G-quadruplex and the structural impact of synthetic non-proteinogenic amino acids on serum albumins: implications for potential intrinsic c-Myc-associated anticancer activity and drug delivery systems. Molecular Therapy:Nucleic Acid. 2025. |