Bioactivity | Anticancer agent 234 (Compound 10) is a modulator for cholinesterase. Anticancer agent 234 inhibits the proliferation of liver cancer cell Hep3B and SkHep1 with IC50 of 3.6 and 19.9 μM. Anticancer agent 234 exhibits a low embryonic toxicity in zebrafish models (10-15 μM)[1]. |
Formula | C26H26ClN3O2S |
Molar Mass | 480.02 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Kisla M M, et al. Synthesis and Structure of Novel Phenothiazine Derivatives, and Compound Prioritization via In Silico Target Search and Screening for Cytotoxic and Cholinesterase Modulatory Activities in Liver Cancer Cells and In Vivo in Zebrafish[J]. ACS Omega, 2024. |