Bioactivity | Anticancer agent 230 (example 65) is a caseinolytic protease P (ClpP) activator with anticancer activity. Anticancer agent 230 is able to induce the degradation of mitochondrial proteins in SUM159 and MDA-MB-231 triple-negative breast cancer cells in a time-dependent manner[1]. |
CAS | 2485052-87-5 |
Formula | C22H19ClN4O |
Molar Mass | 390.87 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Preparation of tetrahydropyrido[4,3-d]pyrimidine-2,4-dione analogs useful in the treatment of cancers and in modulating the activity of caseinolytic protease p function. United States, US20230339947 A1. 2023-10-26. |