Bioactivity | Anticancer agent 225 (Comp 51) is a triterpenoic acids analogue which exhibits suppressive effect on elimination of different type of cancer stem cells (CSCs) and increase the ROS level of CSCs. Anticancer agent 225 can be used for cancer research[1]. |
Invitro | Anticancer agent 225 对 A375 和 B16F10 细胞的 IC50 分别为 2.4 和 1.59 μM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Anticancer agent 225 相关抗体: |
In Vivo | Anticancer agent 225 (5 mg/kg, 腹腔注射, 每日一次共 15 d) 对 C57BL/6 和 Balb/C 裸鼠的肿瘤生长有抑制作用[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
CAS | 2251753-61-2 |
Formula | C41H59N3O3S |
Molar Mass | 673.99 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Liu X, et al. Synthesis and Discovery Novel Anti-Cancer Stem Cells Compounds Derived from the Natural Triterpenoic Acids. J Med Chem. 2018 Dec 13;61(23):10814-10833. |