Bioactivity | Anticancer agent 223 (Compound V-d) is an anticancer agent that triggers cell death through caspase-dependent and caspase-independent mechanisms. Anticancer agent 223 inhibits tumor spheroid formation and resensitizes cisplatin (HY-17394)-resistant A2780 cells to cisplatin (HY-17394) treatment[1]. |
CAS | 1328150-75-9 |
Formula | C20H19ClN4O |
Molar Mass | 366.84 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Thuy Lu Vo T, et al. Design, synthesis and biological evaluation of novel quinazoline derivatives as immune checkpoint inhibitors. Bioorg Med Chem Lett. Published online May 15, 2024. |