| Bioactivity | Anticancer agent 192 (compound XXI) is a steroid-based histamine H3 receptor antagonist with no affinity for muscarinics and hERG. Anticancer agent 192 is quite stable in human and rat liver microsomes. Anticancer agent 192 can improve the cognitive level and reduce the degree of addiction in rats in the in vivo addiction test[1]. |
| Formula | C26H38N2O2 |
| Molar Mass | 410.59 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ledneczki I, et al. Discovery of Novel Steroid-Based Histamine H3 Receptor Antagonists/Inverse Agonists. J Med Chem. 2024 Feb 23. |