| Bioactivity | Anticancer agent 147 (compound 6j) is a derivative of sophoridine (HY-N1373) and is a ferroptosis inducer. Anticancer agent 147 can promote the accumulation of intracellular Fe2+, reactive oxygen species (ROS) and MDA, increase ER stress, and upregulate the expression of the activating transcription factor ATF3. Anticancer agent 147 has good anti-liver cancer effects in vitro and in vivo[1]. |
| Name | Anticancer agent 147 |
| CAS | 2241283-11-2 |
| Formula | C32H40BrN3O2 |
| Molar Mass | 578.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Tian K, et al. Sophoridine derivative 6j inhibits liver cancer cell proliferation via ATF3 mediated ferroptosis. Cell Death Discov. 2023 Aug 14;9(1):296.. |
Anticancer agent 147
CAS: 2241283-11-2 F: C32H40BrN3O2 W: 578.58
Anticancer agent 147 (compound 6j) is a derivative of sophoridine (HY-N1373) and is a ferroptosis inducer. Anticancer ag
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