Bioactivity | Anticancer agent 146 (compound 1.19) is a necroptosis inducer. Anticancer agent 146 has anti-tumor efficacy in the mouse MDA-MB-231 xenograft model[1]. |
Invitro | Anticancer agent 146 (compound 1.19) 抑制不同癌细胞系的 IC50s 分别为 8.54 μM (MDA-MB-231),4.24 μM (MCF7),4.67 μM (4T1),8.02 μM (67NR),3.36 μM (MIAPaCa-2),和 1.76 μM (WiDr)[1]。 0 --> Anticancer agent 146 相关抗体: |
Name | Anticancer agent 146 |
Formula | C19H16Cl2N2O2 |
Molar Mass | 375.25 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Schumacher TJ, et al. Synthesis and biological evaluation of benzofuran piperazine derivatives as potential anticancer agents. Bioorg Med Chem Lett. 2023 Sep 1;93:129425.. |