PeptideDB

Anticancer agent 131

CAS: 2864443-47-8 F: C33H24ClN3O5 W: 578.01

HCT-116-IN-1, a γ-lactam-fused pyridone derivative, has anticancer activity and displayed high cytotoxicity against HCT
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Bioactivity HCT-116-IN-1, a γ-lactam-fused pyridone derivative, has anticancer activity and displayed high cytotoxicity against HCT116 cells with an IC50 of 5.59 μM[1].
Name Anticancer agent 131
CAS 2864443-47-8
Formula C33H24ClN3O5
Molar Mass 578.01
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. An YN, et.al. Unexpected Cascade Sequence Forming the C(sp3)-N/C(sp2)-C(sp2) Bond: Direct Access to γ-Lactam-Fused Pyridones with Anticancer Activity. J Org Chem. 2023 Jul 7;88(13):7998-8009.