Bioactivity | HCT-116-IN-1, a γ-lactam-fused pyridone derivative, has anticancer activity and displayed high cytotoxicity against HCT116 cells with an IC50 of 5.59 μM[1]. |
Name | Anticancer agent 131 |
CAS | 2864443-47-8 |
Formula | C33H24ClN3O5 |
Molar Mass | 578.01 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. An YN, et.al. Unexpected Cascade Sequence Forming the C(sp3)-N/C(sp2)-C(sp2) Bond: Direct Access to γ-Lactam-Fused Pyridones with Anticancer Activity. J Org Chem. 2023 Jul 7;88(13):7998-8009. |