Bioactivity | Anticancer agent 124 is an orally active, highly selective and potent pan RAF inhibitor. Anticancer agent 124 inhibits MAPK signalling in BRAF V600E, NRAS and KRAS mutant tumor cells[1]. |
Name | Anticancer agent 124 |
CAS | 1884226-20-3 |
Formula | C26H21ClN4O3 |
Molar Mass | 472.92 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Helen Mason, et al. Abstract 5160: Development of REDX05358, a novel highly selective and potent pan RAF inhibitor and a potential therapeutic for BRAF and RAS mutant tumors. Cancer Res 1 July 2017; 77 (13_Supplement): 5160. |