Anticancer agent 122

CAS: F: C18H15ClN2O2S W: 358.84

Anticancer agent 122, an inhibitor of human lactate dehydrogenase A enzyme (hLDHA), has good anticancer activities and c

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Bioactivity	Anticancer agent 122, an inhibitor of human lactate dehydrogenase A enzyme (hLDHA), has good anticancer activities and can be used for anticancer research[1].
Invitro	Anticancer agent 122 (Compound 8m) (0-100 μM；72 小时) 抑制肝癌细胞 HepG2 细胞和宫颈癌细胞 SiHa 细胞生长，IC50 值分别为 5.15 μM 和 1.65 μM，且对人胚胎肾细胞系 HEK293 细胞无明显毒性[1]。 Cell Cytotoxicity Assay[1] Cell Line:
Name	Anticancer agent 122
Formula	C18H15ClN2O2S
Molar Mass	358.84
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Sharma D, et.al.Design and Synthesis of Thiazole Scaffold-Based Small Molecules as Anticancer Agents Targeting the Human Lactate Dehydrogenase A Enzyme. ACS Omega. 2023 May 10;8(20):17552-17562.