Bioactivity | Anticancer agent 121, an inhibitor of human lactate dehydrogenase A enzyme (hLDHA), has good anticancer activities and can be used for anticancer research[1]. |
Invitro | Anticancer agent 121 (Compound 8j) (0-100 μM;72 小时) 选择性抑制宫颈癌细胞系 HeLa 和 SiHa 细胞生长,且对人胚胎肾细胞系 HEK293 细胞无明显毒性[1]。 Cell Viability Assay[1] Cell Line: |
Name | Anticancer agent 121 |
Formula | C19H18N2O3S |
Molar Mass | 354.42 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sharma D, et.al.Design and Synthesis of Thiazole Scaffold-Based Small Molecules as Anticancer Agents Targeting the Human Lactate Dehydrogenase A Enzyme. ACS Omega. 2023 May 10;8(20):17552-17562. |