| Bioactivity | Antibiofilm agent-13 (compound 14b) is a potent antibacterial agent that displays a broad-spectrum antimicrobial activity. Antibiofilm agent-13 could disintegrate the integrity of bacterial cell membranes by destroying transmembrane potential and enhancing membrane permeability, and causing the generation of intracellular ROS and the leakage of DNA and proteins, ultimately leading to bacterial death. Antibiofilm agent-13 inhibits both Gram-positive bacteria (MIC of 0.5-1 μg/mL) and Gram-negative bacteria (MIC of 1-32 μg/mL)[1]. |
| Formula | C43H56Br2N2O5 |
| Molar Mass | 840.72 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Siyu Yang, et al. Development of membrane-targeting chalcone derivatives as antibacterial agents against multidrug-resistant bacteria. Eur J Med Chem. 2024 Oct 18:280:116969. |
Antibiofilm agent-13
CAS: F: C43H56Br2N2O5 W: 840.72
Antibiofilm agent-13 (compound 14b) is a potent antibacterial agent that displays a broad-spectrum antimicrobial activit
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